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At the beginning of the study, the average weight and BMI of patients was 106 kg and 38 kg/m 2, respectively, with approximately 81% considered severely obese (120% of the 95 th percentile or greater for BMI standardized by age and sex)

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this aligns with the broader goal of identifying modifiable risk factors and assessing whether treating these factors improves outcomes (64)

Semin Cell Dev Biol 144:4154

les personnes atteintes de la maladie de Leber (neuropathie optique hrditaire) : la cyanocobalamine est formellement contre-indique, la mthylcobalamine doit tre privilgie