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Mood symptoms that appear shortly after each dose increase may relate to tolerability problems, appetite suppression, or sleep changes

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Animals were then given an intracranial injection of 40 nmol TAT or TAT-DAT NT , and were immediately returned to open-field chambers for a 60-min recording session

Everything You Need to Know Most patients start noticing reduced appetite within the first week, with visible weight loss beginning around 2-4 weeks