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The discovery that NNMT expression is dramatically elevated in adipose tissue of obese humans and animal models, and that NNMT inhibition or knockdown prevents diet-induced obesity and improves metabolic health, has catalyzed intense research interest in NNMT as a therapeutic target for obesity, metabolic syndrome, and related conditions

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A Reddit user in a BPC-157 forum, Ryan Beattie, told Undark that he decided to try the peptide last year in an effort to live a healthier lifestyle while weaning off the powerful painkillers he had been taking for more than a decade