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Zofran is primarily used to treat nausea and vomiting, especially in situations such as chemotherapy, radiation therapy, or surgery

After the establishment of the dopamine positive reinforcement theory of addiction in the 1970s, multiple nondopaminergic systems have been proposed to play a role in alcohol addiction such as the endogenous opioid positive reinforcement and corticotropinreleasing hormone negative reinforcement theories (Herz, 1997

In this study, we confirmed that TP is implicated in the expression of IL-8 in KB/TP cells (Fig