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In particular, hemocompatibility of blood-contacting devices is tested in vitro in accordance with the ISO standard 10993-4 guidelines, and this testing comprises evaluation of thrombosis, the blood coagulation system, the complement system, and multiple effects on platelets and leukocytes [464]

Temporal changes in baseline characteristics between the later and earlier time periods were evaluated separately for the SGLT2i and GLP-1 RA cohorts using the standardized mean difference (SMD) in the level of each covariate, with SMDs of 0.2, 0.5, and 0.8 considered to correspond to small, medium, and large differences, respectively [20]

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