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Along with muscular weakness, there was progressing intracranial (sinus sagittal superior), portal and caval hypertension, and aortal hypotension, progressing thrombosis, in arteries and veins, both peripherally and centrally, severe ECG disturbances, and severe lesions in the brain, heart, lung, liver, kidney and gastrointestinal tract [80]

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It highlights emerging evidence of the interconnectedness among iron overload, senescence, and fibrosis, examining their potential crosstalk and collective role in disease progression (Fig

MT-2 is an analog of the peptide hormone alpha-melanocyte stimulating hormone