Similarly, the FDA has approved a number of injectable GLP-1s for type 2 diabetes, such as Ozempic (semaglutide), Mounjaro (tirzepatide), and (semaglutide), an oral GLP-1 medication for blood sugar control in people with type 2 diabetes
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Research from peptide discontinuation studies in lipodystrophy populations (the original FDA-approved use case for tesamorelin) showed that visceral adipose tissue began to reaccumulate within 812 weeks after stopping, with the rate of regain correlating inversely to baseline metabolic health
Both matter, especially during TRT
GLP-1 receptor agonists have transformed diabetes care, but the long-term safety of GLP-1 therapies has become an important topic as treatment continues for many years