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Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

Although this review explored multiple antioxidant-enzyme interaction strategies, some of these approaches are still undergoing trials, and their efficacy has not been fully established

The problem is compounded by the fact that even within a given cell, NAD + is compartmentalized, and there is little understanding of which pool is most relevant to outcomes or what governs the subcellular distribution of NAD + (refs