It is also important to note that many ASD studies systematically exclude participants with common comorbidities such as epilepsy, gastrointestinal disorders or severe behavioral dysregulation
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In a randomized, 8-week trial GH significantly increased extracellular water mass in male and female athletes by 10.2% (1.8 kg) and 7.9% (1.2 kg) compared to controls, which was significantly associated with more frequent reports of swelling [54]
Both the STEP and SURMOUNT clinical trials were multicenter, large, placebo-controlled, and randomised studies conducted among individuals with obesity or type 2 diabetes
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