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Thus, these can be used by the meningococcus to evade detection by neutrophils, allowing the infection to proceed

OA Table 2 shows that while they were able to get statistical significance for their primary endpoint (which was a composite of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke,) they did not achieve statistical significance for any of their confirmatory or supportive secondary endpoints, including the individual endpoints from the composite

Marketed under the brand names Mounjaro (for diabetes) and Zepbound (for weight management), tirzepatide has demonstrated significant efficacy in randomized clinical trials

It is a prescription medicine with a defined role in diabetes and obesity care, it can help with glycaemic control and weight reduction, but it can also cause nausea, vomiting, constipation and other gastrointestinal side effects

As a result, recent publications have quantified error-prone steps to help reduce the frequency of persistent errors