In that case, you need to find out the cause with medical advice
A further step toward understanding synaptic plasticity in inhibitory neurons would require knowledge of forms and mechanisms of plasticity that can be induced by natural patterns of activity, typical for each specific type of inhibitory neurons
While supplements are available, whole food sources are generally recommended as a first option
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Do not begin high-dose nutrients, methylfolate, folinic acid, SAMe, methionine or creatine without appropriate professional guidance