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The induction of p70S6K1 phosphorylation was abolished when cells were treated with both BMS-754807 and U0126 (Lane 4), indicating that suppression of MEK1/2 abolishes BMS-754807-induced p70S6K1 phosphorylation

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These mutations were applied equally to each of the Rex domains of Peredox, resulting in a family of constructs termed NAPstars (Supplementary Table 1)

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