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Possible reasons for high levels include, for example: 5 Liver diseases in which the uptake or release of vitamin B12 is altered Kidney dysfunction affecting excretion via urine inflammatory processes in the body certain blood disorders that alter the blood count and vitamin B12 concentration If your blood values remain elevated over a longer period of time without taking high-dose supplements, it is advisable to consult a doctor to determine the underlying causes

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Research shows that targeting NNMT could help in treating these conditions by improving how the body uses energy, reducing fat, and bettering insulin sensitivity