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Peptides have revolutionised modern medicine, with more than 80 peptide drugs approved worldwide and generating over $70 billion in pharmaceutical sales in 2019

Both Wegovy and Ozempic contain the GLP-1 agonist semaglutide, but Wegovy is prescribed for long-term weight management and certain forms of liver disease, while Ozempic is used to control blood sugar in type 2 diabetes and help protect the heart and kidneys

Dynamics of TMD engagement and release could impact the number of cycles of G protein activation that result from a single agonist-binding event