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2 In approximately 20% of patients, MASLD can progress to metabolic dysfunction-associated steatohepatitis (MASH), characterised by inflammation and ballooning degeneration of hepatocytes, which can progress to cirrhosis and hepatocellular carcinoma (HCC)

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Age of onset matters too: AS typically begins before age 40, while degenerative back problems usually start later

Avoid smoking and minimize sun exposure

Compounding pharmacies are required to test high-risk products for evidence of contamination, but those tests are less rigorous than the clinical trials that most drugs go through