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In contrast, at least 1 of the folate receptors, FR-, is expressed in hematopoietic cells and the kidney proximal tubules, among other tissues (Table 2)

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10.1074/jbc.M210664200 J

Health system challenges, particularly in low-resource settings, include limited access to alternative therapies, lack of standardized guidelines, and sociocultural barriers to contraceptive use and pregnancy planning