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Stomach : GLP-1 slows digestion, prolonging satiety (feeling full) after eating

During the initial weeks of retatrutide treatment, the primary experience for most participants in clinical trials was gastrointestinal adjustment rather than dramatic weight loss

Lerner A, Freire de Carvalho J, Kotrova A, Shoenfeld Y (2022) Gluten-free diet can ameliorate the symptoms of non-celiac autoimmune diseases

Novo Nordisk launched the product in the United States in January 2026, marking the first time an oral GLP-1 treatment had been cleared specifically for weight management

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