However, given the lower intracellular GSH:GSSG ratio after IL-13 stimulation, it is difficult to determine the proportionate role that loss of GSH plays in downstream T2-pathway mRNA/protein expression
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Likewise, micronutrients such as zinc (Zn), copper (Cu), and manganese (Mn), key cofactors of antioxidant enzymes, become critical for maintaining redox balance under elevated ROS pressure