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The covalent conjugation of a drug with a biotin ligase enables targeted biotinylation and identification of the drug-bound proteome

However, due to the small sample size (27 in the acupuncture group, 25 in the waiting list group) and the lack of correction for multiple testing, results were not statistically robust

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Nanotechnology-empowered combination therapy for rheumatoid arthritis: principles, strategies, and challenges