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POSTOPERATIVE MANAGEMENT Management options for recurrent or residual MTC include close observation for indolent disease, surgical resection of locoregional disease, EBRT, and local therapies, such as radiofrequency ablation, cryoablation, and embolization, or systemic therapies, such as conventional chemotherapy, kinase inhibitors, and immune checkpoint inhibitors for non-resectable diseases

159 The mitochondrial calcium uniporter (MCU) regulates Ca 2+ in mitochondria, and Ca 2+ uptake by MCU buffers the increase of cytoplasmic Ca 2+ and regulates mitochondrial oxidative phosphorylation

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doi: 10.1530/eje.0.1320012 21 BonertVCarmichaelJWuZMirochaJPerezDAClarkeNJet al

It's thought to work by promoting the formation of new blood vessels (angiogenesis), which improves blood flow and facilitates quicker healing