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Genetic predisposition plays a significant role, as does age, with teenagers being particularly susceptible during growth spurts

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L-Carnitine, synthesized from the essential amino acid lysine, plays a crucial role in the energy production from branched-chain amino acids, essential for optimal body function

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This has implications for how to design human albumin-fused biologics, as QMP engineering may ensure a long plasma half-life, increased target exposure, and enhanced efficacy, despite potential C-terminal cleavage post-administration