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While direct evidence for Dihexa's effects on neurogenesis remains limited, the HGF/c-Met system that Dihexa activates is known to stimulate stem cell differentiation and promote neurogenesis in the adult hippocampus

Tubular epithelial fibroblast transdifferentiation (TEMT) has been proposed as a viable therapeutic option to decrease RF since it stimulates the expression of several fibro-cytokines, which represent a critical mechanism in the development of RF (Li et al., 2004

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Supplementation of cystine suppressed the ISR as evidenced by the reduction of phospho-eIF2 (S51) and ATF4, but rapamycin treatment had no discernible effect (Fig

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