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Side Effect Profile Both medications have similar side effect profiles, with gastrointestinal issues being the most common: Nausea Diarrhea Vomiting Constipation Abdominal pain While the incidence of side effects is generally similar between the two medications, some studies suggest that tirzepatide may have a slightly higher rate of gastrointestinal side effects, particularly at higher doses

But what about people who take semaglutide for months or years

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Molecular Metabolism 45:101165

By 2024, the therapy had been approved in over 60 countries, and Vertex secured favorable pricing and access deals, including a key agreement with the UKs National Institute for Health and Care Excellence (NICE) that extended coverage to more patients