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Background technique [0002] Semaglutide, a long-acting GLP-1 analog developed by Nove Nordisk for subcutaneous injection once a week, was approved by the US FDA on December 5, 2017

Abstract Depression is considered a multifaceted and intricate mental disorder of growing concern due to its significant impact on global health issues

Experiments have shown that female mice lacking Ambra-1 displayed autism-like behavior, supporting the findings of inhibited autophagy in ASD [286]

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It is a structural component of many transcription factors and DNA repair enzymes, including p53, AP-1, and polymerases