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However, due to its rapid dedifferentiation in vitro and the need to obtain ethical permission for specimen acquisition, these reasons limit the use of primary hepatocytes

Patent expiry dates and market entry timelines are estimates based on publicly available data and are subject to change based on litigation outcomes, regulatory decisions, and market conditions.

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Exposure in healthy Chinese subjects was slightly higher than that seen in other populations (including healthy European and Japanese subjects and obese European subjects, Fig