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Taking more than the recommended dose can lead to an overdose, which can be serious and may require immediate medical attention

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As such, liver disease may lead to increased ROS production and, subsequently, increased peroxidation of lipid membranes and inflammatory factors production, leading to hepatocyte injury and cell death (6063)

The 2024 Yang paper in Journal for ImmunoTherapy of Cancer documented NNMT in cancer-associated fibroblasts driving tumour progression (PMID 39067875)

We propose that the tumor suppressor p53 may play a role in the pathophysiological process of OA through a bidirectional regulation of cell fate mechanism