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doi: 10.1371/journal.pone.0036216

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15, 2025 from Hirsch, L

Gut IEL GLP-1R mediates local antiinflammatory actions in the small intestine by inhibiting proximal T cell receptor (TCR) signaling in a protein kinase Adependent manner, reducing phosphorylation of ZAP70 and SLP-76, which are key signaling nodes for initiating TCR-driven cytokine expression (Figure 3)

The results were actually quite remarkable 64% of women taking ALC+Clomid ovulated versus 17% of those taking Clomid alone, the number of mature follicles was an average of 2.2 in the ALC+C group versus 0.16 in the Clomid only group, fewer days were needed for follicular maturation, uterine lining was thicker by more than 3mm (that is HUGE, especially given the propensity of Clomid to thin the lining!!), progesterone during the luteal phase was 30% higher, and the pregnancy rate was 49% with ALC+Clomid versus 1% with Clomid alone