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When vitamin B12 levels are low, these processes slow down, leading to a wide range of symptoms

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(3) In naturally aged mice, FOXO4-DRI treatment reduced senescent cell burden, improved liver and kidney function, restored exercise tolerance (grip strength and running capacity), and improved coat appearanceall markers of healthier aging

Transgenic mice in which GCLC expression is abolished in hepatocytes have 58% of normal hepatic GSH levels and manifest liver pathologies characteristic of the various clinical stages of fatty liver disease 8,9

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