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Retrieved June 18, 2023 from National Center for Biotechnology Information (2023)

doi: 10.1016/j.metabol.2023.155659 33 Fernandez-GarciaVGonzalez-RamosSMartin-SanzPCastrilloABoscaL

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Containers should be sealed tight when not in use to prevent moisture exposure and contamination that can affect research outcomes

Potential considerations include: Theoretical concern about promoting angiogenesis in existing tumors (not demonstrated but mechanistically plausible) Possible interactions with dopaminergic medications Limited human safety data due to absence of completed clinical trials GHK-Cu Side Effects# GHK-Cu has an established safety profile, particularly for topical use: Topical formulations are generally well-tolerated with low irritation potential Allergic reactions are rare but possible, particularly in individuals with copper sensitivity Injection site reactions (redness, swelling) can occur with subcutaneous administration No significant systemic side effects reported at standard research doses The extensive commercial use of GHK-Cu in cosmetic products provides a broader real-world safety dataset compared to BPC-157