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Fibroblasts are specialized cells deemed essential in producing new collagen fibers, vital components for structural support in various tissues

The authors also point out that in some rare genetic disorders of B12 metabolism, the active forms may be required, and that smokers, who tend to have an excess of thiocyanate in their blood, may benefit from a taking a form other than cyano-B12

Injections of micronutrient B12 at larger doses may be necessary for older persons to keep their vitamin levels appropriate

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