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But heres what most articles wont tell you upfront: its still investigational

doi: 10.1053/j.gastro.2016.12.050 106 BerthoudHRNeuhuberWL

Dapagliflozin, when used as a component of XIGDUO XR, is indicated in adults with type 2 diabetes mellitus to reduce the risk of: Sustained eGFR decline, end-stage kidney disease, cardiovascular death, and hospitalization for heart failure in patients with chronic kidney disease at risk of progression

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Structured exercise, adequate sleep, and targeted use of probiotics and selected nutraceuticals provide additional, evidence-informed levers to complement pharmacological GLP-1RAs or to support metabolic health in individuals who are not using these medications