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However, for certain drugs and/or formulations, such as those with modified release, prolonged absorption, and multicompartment distribution, t 1/2z may not accurately reflect how long the drug persists in the body or the actual time required to reach steady state
For instance, researchers have experimented with CAR-T cells overexpressing PGC-1 (the transcriptional coactivator that drives mitochondrial biogenesis)
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But those numbers dont apply to patients using weight loss drugs
doi: 10.3389/fpls.2021.707127 Received 09 May 2021 Accepted 30 September 2021 Published 05 November 2021 Volume 12 - 2021 Edited by Gisele Passaia Prietsch, Independent Researcher, Vancouver, BC, Canada Reviewed by Andreia Carina Turchetto Zolet, Federal University of Rio Grande do Sul, Brazil
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