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Tail vein blood glucose concentrations were measured using a handheld glucometer (Contour XT, Bayers) at 0, 15, 30, 60 and 120 min after injection (for the Mc4r KO study a 90 min timepoint was also included)

95% CI: 95% confidence interval

Targeted degradation of transcription coactivator SRC1 through the Ndegron pathway

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Metabolic, Kidney, Hydration, and Electrolyte Testing Comprehensive Metabolic Panel Test CMP Basic Metabolic Panel Kidney Profile Kidney Profile Test Expanded The CMP provides broad metabolic, kidney, glucose, electrolyte, and liver-related information, while the Kidney Profile includes creatinine, eGFR, and urine albumin-related testing