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Blocking NNMT is expected to raise SAM availability, but SAM participates in many cellular processes, so research must establish that selectively raising it does not perturb other methylation pathways

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The benefit would be that the surgeon can feel the uterus with their hands to sometimes remove many smaller fibroids for a myomectomy that may not have been found otherwise

This approach responds more effectively to individual differences and patient disease changes, enhancing targeted treatment

doi: 10.1038/s41591-018-0309-y