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If these intermediates build up faster than the Krebs cycle can process them, they become highly toxic, effectively choking the mitochondria and halting the entire energy-producing apparatus

At the time, concern was expressed that the dense arrangement of genes in the gli cluster raised some uncertainty about the specific role of gliT in mediating self-protection against gliotoxin, however, Schrettl et al

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A low-fat, low-fiber diet made up of small, frequent meals with soft or blended textures works best for most people