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Advantages: - Once-weekly convenience for most formulas - Well-studied efficacy and safety data - More consistent absorption - Compounded versions available at lower cost Considerations: - Requires self-injection or provider administration - Needles can be a barrier for some patients Oral semaglutide (Rybelsus) is currently the only FDA-approved oral GLP-1 medication

In both traditional feeforservice and valuebased health delivery models, GMVs can increase access to healthcare professionals, promote indepth, unrushed medical visits, promote social connection and support, and improve individual engagement and outcomes [206]

This maintains muscle-protective nutrition while minimizing digestive stress

Glia 68 , 22772299 (2020)

Se is ingested as inorganic selenides or selenates, the main Se source in soils, this being reduced to selenite which is metabolized to selenide (H 2 Se) via selenodiglutathione and glutathione selenopersulfide