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doi: 10.2174/1874467213666200611142438 76

, gravitational, centrifugal, etc.) in the presence or the absence of 3D matrices ( in vitro preclinical models to clinical applications ( In the context of in vitro models, a significant milestone is marked by the development of organ-on-chip (OoC) technology since they offer superior control over the cellular microenvironment, enable dynamic perfusion and mechanical stimulation, support real-time monitoring, and allow multi-tissue integration with higher reproducibility compared to organoids and spheroids ( OoC are microfluidic devices generally fabricated exploiting techniques common to microelectronics, such as photolithography ( in vivo ( Figure 1

In contrast, in the Si-DSS group, the number of activated neurons was significantly reduced

RFW: 0.160 g/plant

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