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doi: 10.5772/20932 113 LippiG.DaneseE.MattiuzziC.FavaloroE

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2013, doi: 10.2337/dc12-0706

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Interestingly, both p53 and FOXO control a distinct set of genes that are not targets of Nrf2 activity, even though all three factors induce HMOX1 expression and, therefore, Fe(II) storage and secretion, that plays a role in breast tumorigenesis, highlighting the role of antioxidants in cancer promotion 28