Figure 1: Chemical structure of Glutathione [source: Accessed: 10 Oct 2012] The presence of the reactive sulphydryl group (originating from the cysteine residue) gives rise to GSHs nucleophilic nature and so it reacts readily with electrophiles which can present high risk of toxicity to the cell by causing oxidative damage such as lipid peroxidation to cell membranes, and interfering with the activity of essential proteins and DNA synthesis
Instead, the resin should be immersed in a saturated saline solution and stored in a cool, well-ventilated place, avoiding both freezing and direct sunlight
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Metformin side effects Metformin commonly causes mild side effects, such as: Diarrhea Nausea or vomiting Gas Weakness Indigestion Abdominal discomfort Headache In rare cases, metformin causes serious side effects, including lactic acidosis, vitamin B12 deficiency, and allergic reactions
Theyre not the most common side effect, but they do affect around 515% of people, especially early on or during dose increases
