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TD is associated with a dramatic reduction of pancreatic thiamine content by up to 75% (89)

Cagrilintide + Tirzepatide Storage & Handling Storage Reference (Both Compounds) State Lyophilized (long-term) Tirzepatide -4 F (-20 C), 12+ months Cagrilintide -4 F (-20 C), 12+ months State Lyophilized (short-term) Tirzepatide 35.6-46.4 F (2-8 C), several months Cagrilintide 35.6-46.4 F (2-8 C), several months State Reconstituted (liquid) Tirzepatide 35.6-46.4 F (2-8 C), 28-30 days Cagrilintide 35.6-46.4 F (2-8 C), 28-30 days State Color when reconstituted Tirzepatide Clear, colorless Cagrilintide Clear, colorless State Shake

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Agarose with control cells was melted and processed, as indicated, immediately after the cooling step

Chetty AK et al