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Its effects are sustained over seven days, which is why most patients are advised to inject semaglutide once per week

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Wilcken B, Wiley V, Sim KG, Carpenter K

However, this also allowed pharmacies to offer these drugs at lower costs

Nevertheless, the direction of effect was consistent: 15 of 18 individual point estimates lay on the increased-risk side of the null, and the pooled result remained statistically significant under both the DerSimonianLaird and restricted maximum-likelihood estimators