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The orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids

Special Considerations for Patients With a History of Gallstones If you have a history of gallbladder disease, you should be especially cautious when considering or using GLP-1 medications

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Patients should get prescriptions from their doctors and fill them at state-licensed pharmacies

A history of a serious hypersensitivity reaction to saxagliptin, metformin HCl, or any of the ingredients in saxagliptin and metformin hydrochloride extended-release tablets