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Plasmids for all WD40 mutants (WD40 Arg13Ala, Lys15Ala, Arg300Ala, and WD40 Tyr33Ala, Lys17Ala) were generated either using the Q5 Site-Directed Mutagenesis Kit (New England Biolabs, USA) or were synthesized by TOPGENE Technologies (Canada) and were purified as described above

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Consequently, low activation prevented proliferation in vitro (Supplementary Fig

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Direct effect of the synthetic analogue of glucagon-like peptide type 1, liraglutide, on mature adipocytes is realized through adenylate-cyclase-dependent enhancing of insulin sensitivity

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