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These autoantibodies against immunomodulatory proteins (including cytokines, chemokines, complement components and cell-surface proteins) could attack tissues of patients, thereby impair host cell signals, perturb immune function, damage organ systems, and increase COVID-19 severity 36

Treatment of inflammatory bowel disease: a comprehensive review

Cellular mechanisms and tissue effects IGF-1 LR3 binding to IGF1R triggers autophosphorylation rapidly

Given their biological antioxidant function, the antioxidant genes in the glutathione S-transferase (GST) family are believed to be associated with development and progression of asthma

Singh AK, James G, Anker SD, et al