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Consequently, a positive feedback loop is established, which amplifies the inflammatory process [194, 195]

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HUBERMAN: Now, this can be a good thing if you're trying to upregulate growth hormone receptors at a given injury site so that growth hormone, which comes from the pituitary, and then we'll talk a bit about more later, then can have a heightened level of action at that tissue and growth hormone is involved in tissue turnover and repair

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iii) the ASK1/c-Jun N-terminal kinase (JNK) pathway, mediating redox-sensitive apoptosis and autophagy (165)