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DSIP was first characterized by Marcel Monnier and colleagues at the University of Basel, Switzerland, arising from a series of cross-circulation experiments in which blood from a sleeping rabbit was transferred to an awake recipient, causing measurable changes in the recipient's EEG brainwave patterns consistent with delta-wave sleep induction

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If excessive cells die in tissues, serious Cardio-Cerebrovascular Diseases would occur, namely, hypertension, myocardial infarction, and ischemic stroke

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