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(2023) New England Journal of Medicine n=338 Phase 2 trial showing retatrutide produced up to 24.2% body weight loss at 48 weeks, surpassing tirzepatide results

Solutions Focus on calorie-dense protein sources: fatty fish, whole eggs, higher fat dairy, protein powder Use liquid calories strategically: protein shakes, smoothies, milk digest more easily than solid food Time higher calorie meals for windows when appetite is strongest (often morning for many users) Consider dose reduction if appetite suppression is preventing adequate nutrition Set phone reminders to eat every 3 hours regardless of hunger signals Challenge: Energy Fluctuations Affecting Training Some users experience periods of reduced energy, particularly during early adaptation or immediately following dose increases

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