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Oral dosing is viable especially for GI-specific issues -- ulcers, IBD, NSAID-induced gut damage (Sikiric, 1999)
Briefly, 80 l of 67 mM potassium phosphate buffer (NaH 2 PO 4 -Na 2 HPO 4 , pH6.8), 25 l of desired concentration of inhibitor solution and 125 l of 5 mM L-tyrosine were mixed and added into each well of a 96-well Elisa plate, incubated at 25C for 5 minutes
Histamine-related symptoms can overlap with food allergy, chronic urticaria, mast-cell disorders, medication reactions, migraine, dysautonomia and gastrointestinal disease
R.GriffithO
Methods This was a prospective, randomized, interventional clinical study
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