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In contrast to earlier GLP-1 receptor agonists, which primarily target appetite suppression and glycemic improvement, GLP-3 leverages GCG receptor activation to stimulate lipolysis and elevate basal metabolic rate, thereby contributing to a more pronounced and sustained reduction in adiposity as observed in research models

PMID: 26784461

Caffeine activates mouse TRPA1 channels but suppresses human TRPA1 channels

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Vitamin E acts as a regulator of cellular metabolism, and its deficiency leads to anaemia, dysregulation of energy metabolism, irregular mitochondrial function, and tissue damage resulting from increased lipid peroxidation (170)