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Acknowledgments I thank Lily Lu, MD, PhD for her critical comments and David Liu and Erika Liu for their assistance with editing

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Glutamine can undergo deamidation, while aspartic acid may isomerize to isoaspartic acid, affecting stability

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The parallel with other GLP-1 compounds is instructive

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Diabetologia 58 , 17591768 (2015)

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Phase 3 trial completion timeline Seven Phase 3 trials are expected to report results during this year

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